There is a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to lower afferent agony transmission and create analgesia. For that reason, medications like clonidine that goal alpha-2 receptors can influence the transmission of ache. One of several theories https://thebookmarklist.com/story19752965/top-guidelines-of-onolidine