There exists a launch of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors from the dorsal horn to minimize afferent discomfort transmission and produce analgesia. Therefore, medications like clonidine that goal alpha-two receptors can impact the transmission of pain. May be specified as monotherapy or as https://carolynf725duc9.wikiconversation.com/user