Here, we demonstrate that conolidine, a all-natural analgesic alkaloid Utilized in traditional Chinese drugs, targets ACKR3, thus supplying supplemental proof of the correlation involving ACKR3 and ache modulation and opening alternative therapeutic avenues with the cure of Long-term ache. We shown that, in contrast to classical opioid receptors, ACKR3 https://margaretl727xel0.wikiexpression.com/user